- Tested materials & method
- Synthetic tetrapeptide analogues, including peptide 1 (Ac-His-d-Phe-Arg-Aia) and peptide 3 (Ac-His-pCF₃-d-Phe-Arg-Aia). Laboratory receptor-activity testing and molecular docking; not a human skincare trial.
- What was measured
- Potency and selectivity at human melanocortin receptor subtypes—how strongly a peptide activates a receptor, and which receptor it favors.
- Main finding
- Peptide 1 showed greater selectivity for hMC1R (EC₅₀ 11.2 nM); peptide 3 favored hMC4R (EC₅₀ 4.1 nM). The results illustrate why the exact peptide structure matters.
- What it means here
- This is related research, not a test of PeptiLIFT™ or PeptiPROTECT™. The named peptides are not identified here as Peptide G63™, and these results do not establish a cosmetic benefit from either finished formula.